使用麻醉性镇痛药辅助全身麻醉。
Supplementation of general anaesthesia with narcotic analgesics.
作者信息
Holmes C M
出版信息
Br J Anaesth. 1976 Sep;48(9):907-13. doi: 10.1093/bja/48.9.907.
PMID:786349
Abstract
Four analgesic drugs--fentanyl, phenoperidine, morphine and pethidine--were compared in a double-blind trial involving 113 patients paralysed and ventilated with nitrous oxide and oxygen. The differences between the drugs were relatively small. There were only slight differences in "duration of action", a term which is questioned in this context. Pethidine appeared to have a slightly longer duration of action than the other drugs. The problems inherent in studying analgesics in this manner are discussed.
摘要
在一项双盲试验中，对113名使用氧化亚氮和氧气进行麻痹和通气的患者，比较了四种镇痛药——芬太尼、苯哌利定、吗啡和哌替啶。药物之间的差异相对较小。“作用持续时间”方面只有细微差异，而这一术语在本文中受到质疑。哌替啶的作用持续时间似乎比其他药物略长。本文讨论了以这种方式研究镇痛药所固有的问题。
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