精胺可稳定晶体中苯丙氨酸转运核糖核酸（tRNAPhe）的构象。

Spermine stabilizes the conformation of tRNAPhe in crystals.

作者信息

Prinz H, Furgac N, Cramer F

出版信息

Biochim Biophys Acta. 1976 Sep 20;447(1):110-5. doi: 10.1016/0005-2787(76)90101-5.

Abstract

Crystals from yeast tRNAPhe were dissolved and compared with tRNAPhe that had not been srystallized. A number of differences were found regarding the interaction with ethidium bromide, the melting point and the circular dichroic signal. These differences were assigned to the presence of spermine in the dissolved crystals indicating a transient stabilization of the conformation of tRNAPhe, probably as a tRNAPhe-spermine complex, after dissolving.

摘要

将酵母苯丙氨酸转运核糖核酸（tRNAPhe）晶体溶解，并与未结晶的tRNAPhe进行比较。在与溴化乙锭的相互作用、熔点和圆二色信号方面发现了一些差异。这些差异归因于溶解晶体中精胺的存在，这表明溶解后tRNAPhe的构象可能以tRNAPhe - 精胺复合物的形式暂时稳定下来。