Wagner W H, Yellin A E, Weaver F A, Stain S C, Siegel A E
Division of Vascular Surgery, University of Southern California, Los Angeles.
Ann Vasc Surg. 1994 Nov;8(6):557-65. doi: 10.1007/BF02017412.
During a 20-year period from 1973 to 1992, 109 patients underwent early operation for acute popliteal artery trauma. Clinical variables were analyzed for their association with amputation. Gunshot wounds accounted for the majority of injuries (73%), followed by shotgun wounds (18%), stab wounds (6%), iatrogenic injuries (2%), and lacerations (1%). Fasciotomies were performed selectively in 41% of patients. Seven patients (6%) lost the injured extremity despite arterial repair. The mean time from injury to arterial repair was not significantly different for patients with or without subsequent amputation (8.6 +/- 3.6 and 9.7 +/- 7.4 hours, respectively; p = 0.69). Delay in diagnosis longer than 6 or 12 hours after the injury did not increase the risk of amputation. Other factors not associated with limb loss were preoperative ischemic neurologic deficit or compartmental hypertension, concomitant fracture, and popliteal vein injury. Severe soft tissue injury (p < 0.0001) or postoperative wound sepsis (p < 0.0001) substantially increased the risk of amputation. Delayed fasciotomies were uncommon (4%) but were associated with a significantly increased risk of amputation (p < 0.0001). Vein grafting for arterial repair (p = 0.0017) and shotgun injuries (p < 0.0001) were associated with amputation to the extent that they were related to severe soft tissue injury. The degree of soft tissue trauma and subsequent infection of devitalized tissue limits the success of popliteal arterial repair. Changes in the mechanism of trauma, liberal use of four-compartment fasciotomies, and aggressive management of soft tissue injury resulted in a significant decline in the amputation rate from 21% (4/19) in the first 5 years to 0% (0/39) in the last 5 years of the study.
在1973年至1992年的20年期间,109例患者因急性腘动脉创伤接受了早期手术。分析了临床变量与截肢的相关性。枪伤占损伤的大多数(73%),其次是散弹枪伤(18%)、刺伤(6%)、医源性损伤(2%)和撕裂伤(1%)。41%的患者选择性地进行了筋膜切开术。尽管进行了动脉修复,仍有7例患者(6%)失去了受伤肢体。受伤后至动脉修复的平均时间在截肢和未截肢患者之间无显著差异(分别为8.6±3.6小时和9.7±7.4小时;p = 0.69)。受伤后诊断延迟超过6或12小时并未增加截肢风险。与肢体丧失无关的其他因素包括术前缺血性神经功能缺损或骨筋膜室高压、合并骨折以及腘静脉损伤。严重软组织损伤(p < 0.0001)或术后伤口感染(p < 可见0001)显著增加了截肢风险。延迟筋膜切开术并不常见(4%),但与截肢风险显著增加相关(p < 0.0001)。用于动脉修复的静脉移植(p = 0.0017)和散弹枪伤(p < 0.0001)在与严重软组织损伤相关的程度上与截肢有关。软组织创伤的程度以及失活组织的继发感染限制了腘动脉修复的成功率。创伤机制的变化(此处原文有误,推测应为“创伤机制的改变”)、四室筋膜切开术的广泛应用以及对软组织损伤的积极处理导致截肢率从研究前5年的21%(4/19)显著下降至最后5年的0%(0/39)。