Experimental research on endotoxic shock in urology.

The endotoxic shock in urological surgery is more frequent due to the increased incidence of the gram-negative infections. More toxic than septic it suggests the hypothesis of a generalized Sanarelli-Schwartzman hypersensitivity phenomenon with hypercoagulation and microthromboses of small vessels. The hypothesis experimentally tested hold good in most cases at the same time requiring an anti-coagulant therapy as an improving effect.