Geiss H K
Institute of Hygiene, University of Heidelberg, Germany.
Endosc Surg Allied Technol. 1994 Oct;2(5):276-8.
It has been well established that instruments for minimally invasive surgery (MIS) must be treated like ordinary surgical instruments when they are intended for use within sterile areas of the human body. Due to the special design of most MIS instruments autoclaving (i.e. application of heat) may damage these delicate items. Therefore, low temperature sterilisation processes are essential. Gas sterilisation with ethylene oxide and formaldehyde may pose significant health hazards to workers exposed to these gases and to patients due to residues remaining on the surface of the instruments. Their general use in hospitals is more and more discouraged. However, with the advent of hydrogen peroxide gas plasma sterilisation there is a true alternative available for the sterilisation of MIS instruments. In contrast, the use of immersion sterilants such as liquid glutaraldehyde or peracetic acid cannot be considered as adequate because it is almost impossible to keep the processed instruments sterile until their intended use.
已经明确的是，当微创手术（MIS）器械打算在人体无菌区域内使用时，必须像普通手术器械一样进行处理。由于大多数MIS器械的特殊设计，高压灭菌（即加热）可能会损坏这些精密物品。因此，低温灭菌工艺至关重要。环氧乙烷和甲醛气体灭菌可能会对接触这些气体的工作人员以及患者造成重大健康危害，因为器械表面会残留这些物质。医院越来越不鼓励普遍使用它们。然而，随着过氧化氢气体等离子体灭菌技术的出现，对于MIS器械的灭菌有了一种真正的替代方法。相比之下，使用诸如液态戊二醛或过氧乙酸等浸泡消毒剂并不足够，因为几乎不可能使处理过的器械在使用前保持无菌状态。
