Handley J, Burrows D
Department of Dermatology, Royal Victoria Hospital, Belfast, N. Ireland, UK.
Contact Dermatitis. 1994 Nov;31(5):288-90. doi: 10.1111/j.1600-0536.1994.tb02020.x.
The case is reported of a 28-year-old man who developed allergic contact dermatitis from 2 synthetic fragrance ingredients, Lyral (3- and 4-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-aldehyde) and acetyl cedrene, in separate underarm deodorant preparations. The implications of the patient's negative patch test reactions to the European standard series (Trolab) and cosmetics and fragrance series (both Chemotechnique Diagnostics) are discussed. The importance is stressed of patch testing with the patient's own preparations when cosmetic dermatitis is suspected, and of identifying and reporting offending fragrance ingredients, with a view possibly to updating the European standard series and commercially available cosmetics and fragrance series.
报告了一例28岁男性病例，该患者在两种不同的腋下除臭剂制剂中，因两种合成香料成分——莱莉醛（3-和4-(4-羟基-4-甲基戊基)-3-环己烯-1-醛）和乙酰雪松烯，发生了过敏性接触性皮炎。讨论了该患者对欧洲标准系列（Trolab）以及化妆品和香料系列（均为Chemotechnique Diagnostics公司产品）斑贴试验呈阴性反应的意义。强调了在怀疑有化妆品皮炎时，对患者自用制剂进行斑贴试验的重要性，以及识别和报告引起过敏的香料成分的重要性，以期可能更新欧洲标准系列以及市售化妆品和香料系列。
