Calhoun D A, Mutinga M L, Wyss J M, Oparil S
Division of Cardiovascular Disease, University of Alabama at Birmingham 35294.
J Hypertens. 1994 Nov;12(11):1291-6.
To compare muscle sympathetic nerve activity (MSNA) in age- and weight-matched African-Americans and American Caucasians with primary hypertension.
Using microneurography, we compared MSNA at rest and in response to cold-pressor testing and handgrip exercise in 13 hypertensive African-Americans and 12 hypertensive American Caucasians.
All subjects were withdrawn from antihypertensive medications for at least 2 weeks before the study. MSNA was recorded from the left peroneal nerve.
Resting MSNA was similar in the Blacks and the Caucasians. Increases in muscle efferent activity, mean arterial pressure and heart rate in response to the cold pressure and handgrip exercise were not significantly different in Black and in Caucasian subjects.
MSNA, either at rest or in response to certain laboratory stressors, is not different in Black and in Caucasian hypertensive subjects with similar resting blood pressures.
比较年龄和体重匹配的患有原发性高血压的非裔美国人和美国白种人的肌肉交感神经活动（MSNA）。
我们使用微神经ography术，比较了13名高血压非裔美国人和12名高血压美国白种人在静息状态下以及对冷加压试验和握力运动的反应中的MSNA。
所有受试者在研究前至少停用抗高血压药物2周。从左侧腓神经记录MSNA。
黑人与白人的静息MSNA相似。黑人与白人受试者在冷加压和握力运动后肌肉传出活动、平均动脉压和心率的增加无显著差异。
静息血压相似的黑人与白人高血压患者，其静息或对某些实验室应激源反应时的MSNA并无差异。
