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[激素阉割公猪下丘脑-腺垂体-性腺轴部分的可量化形态动力学。I. 醋酸氯地孕酮处理公猪的研究]

[Quantifiable morphokinesis on parts of the hypothalamo-adenohypophyseal-gonadal axis of hormonally castrated boars. I. Studies on boars treated with chlormadinone acetate].

作者信息

Sajonski H, Dorst J, Busch W, Hagelschuer H

出版信息

Arch Exp Veterinarmed. 1978;32(1):39-44.

PMID:78696
Abstract

A clearly morphokinetic effect was recorded from the parts of the hypothalamo-adenohypophyseo-gonadal axis in boars that had been treated with chloromadinone acetate (CAP). Luteinising hormone release is inhibited by CAP, which is reflected in an increase of luteinising hormone cells in their storage form. This leads to statistically significant decline in androgenic testicular tissue percentage and in the cell nucleus volumes of Leydig's cells. Excessive weight decrease of the testicle is caused primarily by some 60 per cent reduction in tube length. The neurons of the tested hypothalamic nuclear region, that is the nucleus praeopticus medialis, have shown that in treated animals cell nucleus volumes were significantly depressed.

摘要

在接受醋酸氯地孕酮(CAP)治疗的公猪中,下丘脑 - 腺垂体 - 性腺轴各部分记录到明显的形态动力学效应。CAP抑制促黄体生成素释放,这表现为促黄体生成素细胞储存形式增加。这导致雄激素性睾丸组织百分比以及睾丸间质细胞的细胞核体积在统计学上显著下降。睾丸重量过度减轻主要是由于管长度大约减少了60%所致。所测试的下丘脑核区域,即内侧视前核的神经元显示,在接受治疗的动物中,细胞核体积显著减小。

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