Koeslag J H
Department of Medical Physiology, University of Stellenbosch, Tygerberg, South Africa.
J Theor Biol. 1994 Dec 7;171(3):341-5. doi: 10.1006/jtbi.1994.1236.
Koinophilia, the avoidance of sexual mates bearing strange phenotypic features, or displaying odd behaviour, would, if it evolved, profoundly influence the evolutionary process. A stochastic computer model was therefore devised to investigate the evolution of an initially rare koinophilic trait in panmictic populations, subject to mutations with randomly varying fitnesses. Individual genomes consisted of 50 genes. Mutations occurred at a rate of 0.005, 0.01 or 0.02 per gene per generation. The mean and maximum fitness of mutations could be varied, as could the proportion of beneficial mutations. The carriers of the koinophilic trait avoided, with adjustable degrees of intensity, mates displaying unusual phenotypic features (traits with population frequencies < 0.5); panmictic individuals mated randomly. The results show that koinophilia tends to replace panmixis whenever the preference for common phenotypic traits is strongly expressed, when few mutations are beneficial (1% instead of 10%), or when the maximum fitness of mutations is low (1.2 instead of 2.0). The mutation rate and mean fitness of mutations had only minor effects on the relative advantage of koinophilia.
亲交偏好，即避免与具有奇怪表型特征或表现出怪异行为的性伴侣交配，如果这种偏好得以进化，将会深刻影响进化过程。因此，设计了一个随机计算机模型，以研究在随机交配种群中，一种最初罕见的亲交偏好性状在具有随机变化适应度的突变影响下的进化情况。个体基因组由50个基因组成。突变率为每个基因每代0.005、0.01或0.02。突变的平均适应度和最大适应度以及有益突变的比例都可以变化。具有亲交偏好性状的个体以可调节的强度避免与表现出异常表型特征（种群频率<0.5的性状）的配偶交配；随机交配个体则随机交配。结果表明，当对常见表型特征的偏好强烈表达时、有益突变较少（1%而非10%）时，或者当突变的最大适应度较低（1.2而非2.0）时，亲交偏好倾向于取代随机交配。突变率和突变的平均适应度对亲交偏好的相对优势只有较小影响。
