Chen R, Collins S, Remtulla H, Parkes A, Bolton C F
Department of Clinical Neurological Sciences, University of Western Ontario, Victoria Hospital, London, Canada.
Muscle Nerve. 1995 Mar;18(3):330-5. doi: 10.1002/mus.880180311.
Phrenic nerve conduction studies were performed in 50 phrenic nerves from 25 normal subjects using a technique modified from previously described methods. The normal ranges for latency, amplitude, negative peak area, and duration were established. The latency correlates with age and the amplitude increases with chest circumference. With our method, the amplitude increases and the duration decreases with lung volume. We found good right-left agreement and reproducibility. Therefore, the unaffected side can be used as a reference in unilateral phrenic nerve lesions and previous studies can be used for comparison in serial studies. We recommend that phrenic nerve conduction studies be used routinely to diagnose and monitor patients with respiratory involvement from neuromuscular diseases.
采用一种对先前所述方法进行改良的技术，对25名正常受试者的50条膈神经进行了膈神经传导研究。确定了潜伏期、波幅、负峰面积和时限的正常范围。潜伏期与年龄相关，波幅随胸围增加而增大。采用我们的方法，波幅随肺容积增加而增大，时限则减小。我们发现左右两侧结果一致性良好且具有可重复性。因此，在单侧膈神经病变中，健侧可作为参照，在系列研究中可与既往研究进行比较。我们建议常规使用膈神经传导研究来诊断和监测患有神经肌肉疾病且有呼吸受累的患者。
