• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

[Therapy of generalized tendomyopathy (fibromyalgia) caused by blocking 5-HT3 receptors].

作者信息

Stratz T, Schochat T, Hrycaj P, Lacki J, Mennet P, Färber L, Schweiger C, Müller W

机构信息

Hochrhein-Institut für Rehabilitationsforschung, Bad Säckingen.

出版信息

Z Rheumatol. 1994 Nov-Dec;53(6):335-8.

PMID:7871905
Abstract

In more than 40% of patients with fibromyalgia a marked influence on the pain in the skeletal system with a decrease of the tenderness at "tenderpoints" can be achieved by blocking the 5-HT3-receptors with ondansetron or tropisetron-hydrochloride. Physical complaints and vegetative signs also improve. It is discussed if patients not responding to therapy with ondansetron or tropisetron-hydrochloride have to be discriminated as a subgroup of fibromyalgia. More investigations are needed to confirm the described effects.

摘要

相似文献

1
[Therapy of generalized tendomyopathy (fibromyalgia) caused by blocking 5-HT3 receptors].
Z Rheumatol. 1994 Nov-Dec;53(6):335-8.
2
Efficacy and tolerability of tropisetron in primary fibromyalgia--a highly selective and competitive 5-HT3 receptor antagonist. German Fibromyalgia Study Group.托烷司琼在原发性纤维肌痛中的疗效和耐受性——一种高选择性竞争性5-羟色胺3受体拮抗剂。德国纤维肌痛研究组
Scand J Rheumatol Suppl. 2000;113:49-54. doi: 10.1080/030097400446643.
3
[Pilot study with 5-HT3 antagonists. Good outcome in fibromyalgia pain].
MMW Fortschr Med. 2002 Mar 14;144(11):49.
4
Results of the intravenous administration of tropisetron in fibromyalgia patients.曲罗西隆静脉注射治疗纤维肌痛患者的结果。
Scand J Rheumatol Suppl. 2000;113:59-62. doi: 10.1080/030097400446661.
5
Treatment of fibromyalgia with tropisetron, a 5HT3 serotonin antagonist: a pilot study.
Clin Rheumatol. 2000;19(1):6-8. doi: 10.1007/s100670050002.
6
[5-HT3-receptor-antagonists in therapy of rheumatic diseases].
Z Rheumatol. 2003 Feb;62(1):39-41. doi: 10.1007/s00393-003-0479-x.
7
Oral treatment of fibromyalgia with tropisetron given over 28 days: influence on functional and vegetative symptoms, psychometric parameters and pain.用托烷司琼对纤维肌痛进行为期28天的口服治疗：对功能和自主神经症状、心理测量参数及疼痛的影响
Scand J Rheumatol Suppl. 2000;113:55-8. doi: 10.1080/030097400446652.
8
Short-term treatment of primary fibromyalgia with the 5-HT3-receptor antagonist tropisetron. Results of a randomized, double-blind, placebo-controlled multicenter trial in 418 patients.5-羟色胺3受体拮抗剂托烷司琼对原发性纤维肌痛的短期治疗。418例患者的随机、双盲、安慰剂对照多中心试验结果。
Int J Clin Pharmacol Res. 2001;21(1):1-13.
9
[5-HT3 receptor antagonists as a new therapeutic principle in rheumatology?].
Z Rheumatol. 2001 Feb;60(1):47-8. doi: 10.1007/s003930170097.
10
Do predictors exist for the therapeutic effect of 5-HT3 receptor antagonists in fibromyalgia?
Scand J Rheumatol Suppl. 2000;113:63-5. doi: 10.1080/030097400446670.

引用本文的文献

1
The classification of fibromyalgia syndrome.纤维肌痛综合征的分类。
Rheumatol Int. 2007 Sep;27(11):1005-10. doi: 10.1007/s00296-007-0403-9. Epub 2007 Jul 25.
2
[Subgroups of fibromyalgia].[纤维肌痛的亚组]
Schmerz. 2007 Oct;21(5):424-9. doi: 10.1007/s00482-007-0541-8.
3
Ondansetron. A review of its pharmacology and preliminary clinical findings in novel applications.昂丹司琼。其药理学综述及新应用中的初步临床研究结果。
Drugs. 1996 Nov;52(5):773-94. doi: 10.2165/00003495-199652050-00010.