Altbacker V, Zocchi A, Oliverio A, Csányi V
Department of Ethology, Eötvös Loránd University, Göd, Hungary.
Acta Biol Hung. 1993;44(4):321-7.
Intracranial injections of 5 micrograms/fish (equivalent to 2 nmol/g) of the dopamine agonist Apomorphine into the paradise fish brain considerably decrease the occurrence of escape behavior with a parallel increase of time spent in swimming. All other elements of the behavioral repertoire are unaffected. The simultaneous administration of 0.5 micrograms/fish (equivalent to 0.15 nmol/g) of the dopamine antagonist Pimozide abolishes this effect. In a second experiment a dose dependent decrease in escape behavior was obtained with a parallel increase of swimming. On the bases of these pharmacological data it is concluded that the escape and the swimming reactions are truly independent units but their regulation might be closely related.
向天堂鱼脑内注射5微克/鱼（相当于2纳摩尔/克）的多巴胺激动剂阿扑吗啡，可显著减少逃避行为的发生，同时游泳时间相应增加。行为模式的所有其他要素均未受影响。同时给予0.5微克/鱼（相当于0.15纳摩尔/克）的多巴胺拮抗剂匹莫齐特可消除这种效应。在第二个实验中，随着游泳时间的相应增加，逃避行为出现剂量依赖性减少。基于这些药理学数据得出结论，逃避反应和游泳反应是真正独立的单元，但它们的调节可能密切相关。
