Ing E B, Savino P J, Bosley T M, Sergott R C, Kelepouris N
Neuro-ophthalmology Service, Wills Eye Hospital, Philadelphia, PA 19107.
Am J Ophthalmol. 1995 Mar;119(3):376-7. doi: 10.1016/s0002-9394(14)71189-4.
PURPOSE/METHODS: A patient with osteitis deformans (Paget's disease) and hemifacial spasm underwent magnetic resonance tomographic angiography. Bone-modulating bisphosphonates and botulinum injection were administered to treat the hemifacial spasm.
RESULTS/CONCLUSIONS: Computed tomography showed marked temporal bone overgrowth. Magnetic resonance tomographic angiography showed no vascular compression of the facial nerve root. The hemifacial spasm failed to resolve with intravenous pamidronate. Subsequent botulinum injection rendered the patient spasm free for 22 weeks. Further research on the use of bisphosphonates in the treatment of pagetoid hemifacial spasm is required.
目的/方法：一名患有变形性骨炎（佩吉特病）和半面痉挛的患者接受了磁共振断层血管造影。给予骨调节双膦酸盐和肉毒杆菌注射以治疗半面痉挛。
结果/结论：计算机断层扫描显示颞骨明显增生。磁共振断层血管造影显示面神经根部无血管压迫。静脉注射帕米膦酸未能缓解半面痉挛。随后的肉毒杆菌注射使患者在22周内无痉挛。需要进一步研究双膦酸盐在治疗佩吉特样半面痉挛中的应用。
