Crews H M, Ducros V, Eagles J, Mellon F A, Kastenmayer P, Luten J B, McGaw B A
Ministry of Agriculture Fisheries and Food, CSL Food Science Laboratory, Colney, Norwich, UK.
Analyst. 1994 Nov;119(11):2491-514. doi: 10.1039/an9941902491.
Mass spectrometric methods for determining stable isotopes of nutrient minerals and trace elements in human metabolic studies are described and discussed. The advantages and disadvantages of the techniques of electron ionization, fast atom bombardment, thermal ionization, and inductively coupled plasma and gas chromatography mass spectrometry are evaluated with reference to their accuracy, precision, sensitivity, and convenience, and the demands of human nutrition research. Examples of specific applications are described and the significance of current developments in mass spectrometry are discussed with reference to present and probable future research needs.
