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[得普利麻:无需箭毒即可插管]

[Diprivan: intubation without curare].

作者信息

D'Honneur G

机构信息

Hôpital Henri-Mondor, Créteil.

出版信息

Ann Fr Anesth Reanim. 1994;13(4):600-4. doi: 10.1016/S0750-7658(05)80708-7.

Abstract

To intubate under ideal conditions, i.e. with the vocal cords abducted and no motor response to the insertion of the endotracheal tube, the anaesthetist has two alternatives: to use muscle relaxants or to anaesthetize the patient deeply. Apart from cases where muscle relaxants are contra-indicated or required by the type of procedure: Intubation using muscle relaxants means: maintaining the option of varying the depth of anaesthesia, while keeping optimal conditions for intubation; reducing the risk of airways trauma. Intubation without muscle relaxants means: avoiding the risk of allergic complications; producing deep anaesthesia and controlling any resulting haemodynamic effects. The recommended induction agent is propofol, given as a bolus injection at a dose equal to or greater than 2.5 mg.kg-1 in adults and 3.5 mg.kg-1 in children. Alfentanil is the opioid of choice, the dose being between 30 and 40 micrograms.kg-1. Lidocaine, injected as premedication at a dose of 1.5 mg.kg-1 potentiates the effect of alfentanil. The order of injection of the induction agents is important, as it determines the exact moment for laryngoscopy and intubation.

摘要

在理想条件下进行气管插管,即声带外展且对插入气管导管无运动反应时,麻醉医生有两种选择:使用肌肉松弛剂或使患者深度麻醉。除了肌肉松弛剂有禁忌或因手术类型需要的情况外:使用肌肉松弛剂进行气管插管意味着:保持改变麻醉深度的选择,同时保持插管的最佳条件;降低气道创伤风险。不使用肌肉松弛剂进行气管插管意味着:避免过敏并发症的风险;产生深度麻醉并控制任何由此产生的血流动力学效应。推荐的诱导药物是丙泊酚,成人以等于或大于2.5mg·kg-1、儿童以3.5mg·kg-1的剂量静脉推注。阿芬太尼是首选的阿片类药物,剂量为30至40μg·kg-1。利多卡因作为术前用药,以1.5mg·kg-1的剂量注射可增强阿芬太尼的效果。诱导药物的注射顺序很重要,因为它决定了喉镜检查和插管的确切时刻。

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