血浆蛋白水溶液表面张力的温度依赖性。
The temperature dependence of the surface tension of aqueous solutions of plasma proteins.
作者信息
Katona E, Neumann A W, Moscarello M A
出版信息
Biochim Biophys Acta. 1978 Jun 21;534(2):275-84. doi: 10.1016/0005-2795(78)90010-7.
The surface behavior of aqueous solutions of fibrinogen, transferrin, gamma-globulin and albumin at the liquid-gas interface has been investigated by a modified Wilhelmy technique. The temperature dependence of the surface tension was studied over a temperature range of 20--80 degrees C and a pH range of 2--12. Most pronounced conformational changes of fibrinogen with this technique were found in physiological conditions: 35--45 degrees C and pH 7--8. A conformational change was found for gamma-globulin and transferrin solutions, but at a higher temperature and less pronounced than fibrinogen. Albumin did not undergo conformational transitions to a significant extent.
通过改进的威尔海姆技术研究了纤维蛋白原、转铁蛋白、γ-球蛋白和白蛋白水溶液在液-气界面的表面行为。在20-80摄氏度的温度范围和2-12的pH范围内研究了表面张力的温度依赖性。用该技术发现纤维蛋白原在生理条件下（35-45摄氏度和pH 7-8）有最明显的构象变化。发现γ-球蛋白和转铁蛋白溶液有构象变化，但温度更高且不如纤维蛋白原明显。白蛋白在很大程度上没有发生构象转变。
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