Dulfer W J, Govers H A
Department of Environmental and Toxicological Chemistry, Amsterdam Research Institute for Substances in Ecosystems, University of Amsterdam, The Netherlands.
Chemosphere. 1995 Jan;30(2):293-306. doi: 10.1016/0045-6535(94)00390-g.
Experimental data are presented on the enhanced solubilities and micelle/water partition coefficients of 14 polychlorinated biphenyls (PCBs) in solutions of the bile salts sodium taurocholate (TC) and sodium taurodeoxycholate (TDC) below and above the critical micellar concentration (CMC). Solubilities of PCBs in micellar solutions above the CMC depend linearly on bile salt concentration and the solubility enhancement is up to four orders of magnitude. PCB partition coefficients (log Kmw) are independent of bile salt concentrations and are systematically higher in solutions of TDC than in solutions of TC, ranging from 4.26 to 6.24 and from 3.89 to 5.89 respectively. The partitioning behavior of the pertinent extremely hydrophobics between the aqueous and micellar phases is not completely comparable with simple organic solvent/water systems and the correlation between log Kow and log Kmw is non-linear.
本文给出了14种多氯联苯（PCBs）在临界胶束浓度（CMC）以下和以上的牛磺胆酸钠（TC）和牛磺脱氧胆酸钠（TDC）胆盐溶液中的溶解度增强以及胶束/水分配系数的实验数据。CMC以上胶束溶液中PCBs的溶解度与胆盐浓度呈线性关系，溶解度增强高达四个数量级。PCB分配系数（log Kmw）与胆盐浓度无关，且在TDC溶液中系统地高于TC溶液，范围分别为4.26至6.24和3.89至5.89。相关极疏水物在水相和胶束相之间的分配行为与简单有机溶剂/水体系不完全可比，log Kow和log Kmw之间的相关性是非线性的。
