Schatzker J
Department of Surgery, Sunnybrook Health Science Centre, North York, Ont.
Can J Surg. 1995 Feb;38 Suppl 1:S49-54.
The healing response of bone to the injury of implant insertion is similar to its response to fracture. If there is absolute stability between the bone and the implant, the injury to the bone will result in bone formation, the bone growing and conforming to the surface configuration of the implant. There is first appositional bone growth and subsequently bone ingrowth into the interstices of the surface. The newly formed bone is not an uninterrupted layer of bone. It is mixed with well-differentiated fibrous tissue; only 13% to 20% of the bone is in contact with the implant. If the implant is relatively stable after insertion the healing response results in the implant becoming enveloped by dense organized fibrous tissue with occasional areas of fibrocartilage, without any areas of resorption in the surrounding bone. If the implant is unstable after insertion the healing response causes the implant to become surrounded by loosely organized fibrous tissue with active bone resorption occurring in the surrounding bone.
骨对种植体植入损伤的愈合反应与其对骨折的反应相似。如果骨与种植体之间存在绝对稳定性，骨损伤将导致骨形成，骨生长并顺应种植体的表面形态。首先是贴附性骨生长，随后骨长入表面的间隙。新形成的骨不是连续的骨层。它与分化良好的纤维组织混合；只有13%至20%的骨与种植体接触。如果种植体植入后相对稳定，愈合反应会导致种植体被致密的有组织的纤维组织包裹，偶尔有纤维软骨区域，周围骨没有任何吸收区域。如果种植体植入后不稳定，愈合反应会使种植体被疏松组织的纤维组织包围，周围骨出现活跃的骨吸收。
