Tarlo S M, Liss G, Corey P, Broder I
Gage Research Institute, Department of Medicine, University of Toronto, Ontario, Canada.
Chest. 1995 Mar;107(3):634-41. doi: 10.1378/chest.107.3.634.
(1) To compare patients with claims submitted to the Ontario Workers' Compensation Board (WCB) for occupational asthma, in relation to the WCB decisions reached of occupational asthma (OA); aggravation of asthma from irritant exposures (AA); unrelated asthma; no asthma; and (2) to assess determinants of outcome of WCB accepted claims at permanent disability assessments.
A retrospective review of 609 claims submitted to the WCB 1984 to 1988.
The WCB decision reached was OA in 39% of claims, mostly attributed to isocyanates (57% of these). A further 39% were accepted for AA. Exposure to a known sensitizer occurred in 91% with OA and to an irritant in 67% with AA. Forty percent with AA were attributed to a spill or accidental exposure and 68% had preceding asthma. Those with AA were more likely to have clearing of symptoms by the time of their main assessment (43% vs 20% with OA) and were more likely to have remained in the same work (35% vs 20% with OA). Of 200 OA accepted claims reviewed at a mean of 1.9 years later, clearing of asthma occurred in 19% and milder asthma in 47%. Outcome was best with early diagnosis (p < 0.05), and milder impairment of pulmonary function at initial assessment (p < 0.05).
Patients with asthma induced by a workplace sensitizer demonstrate some differences from those related to workplace irritants. Accurate categorization and early removal of those with OA offers the best prognosis.
(1)比较向安大略省工人赔偿委员会(WCB)提交职业性哮喘索赔的患者,与WCB就职业性哮喘(OA)、刺激性物质暴露导致的哮喘加重(AA)、无关哮喘、无哮喘所做出的决定;(2)评估WCB接受的索赔在永久性残疾评估中的结果决定因素。
对1984年至1988年提交给WCB的609份索赔进行回顾性研究。
WCB做出的决定中,39%的索赔为OA,主要归因于异氰酸酯(其中57%)。另有39%因AA被接受。91%的OA患者接触过已知的致敏剂,67%的AA患者接触过刺激性物质。40%的AA患者归因于泄漏或意外暴露,68%既往有哮喘。AA患者在主要评估时更有可能症状缓解(43% vs OA患者的20%),且更有可能仍从事相同工作(35% vs OA患者的20%)。在平均1.9年后对200份被接受的OA索赔进行复查,19%的患者哮喘缓解,47%的患者哮喘较轻。早期诊断(p < 0.05)和初始评估时肺功能损害较轻(p < 0.05)时结果最佳。
工作场所致敏剂诱发的哮喘患者与工作场所刺激性物质诱发的哮喘患者存在一些差异。对OA患者进行准确分类并尽早调离工作岗位可获得最佳预后。