Saint-Marc O, Frileux P, Sales J P, Faucheron J L, Balladur P, Tiret E, Parc R
Centre de Chirurgie Digestive, Hôpital Saint-Antoine, Paris.
Gastroenterol Clin Biol. 1994;18(10):873-9.
Entero-enteral fistulas join a segment affected by Crohn's disease to another which becomes a drainage route and a "victim" of the process. Surgical treatment can be radical (extensive resection of both segments) or conservative (resection of involved bowel and conservation of the "victim"). Fifty-nine patients operated on for Crohn's disease and having 80 entero-enteral fistulas were retrospectively studied.
Main surgical indications were symptomatic intestinal stenosis (56%) or abdominal mass (20%) unresponsive to medical treatment. Fistula was discovered during operation in 33 patients (56%). Conservative treatment was performed in 39 fistulas (49%). In 41 fistulas (51%), proximity of fistulous ends, or Crohn's disease's extension, led to radical treatment. In 66 fistulas (82.5%), histologic examination revealed that Crohn's disease affected only one bowel segment, the other demonstrating only non specific features; in the 14 remaining fistulas (17.5%), Crohn's disease affected both segments.
The clinical presentation of entero-enteral fistulas (non-specific symptoms, frequent peroperative diagnosis), their pathological features (victim segment often free of Crohn's disease) plead for a conservative surgical approach, i.e. adapted to real bowel involvement by Crohn's disease.
肠-肠瘘将受克罗恩病影响的一段肠管与另一段肠管相连,后者成为该病变过程的引流途径和“受害者”。手术治疗可以是根治性的(广泛切除两段肠管)或保守性的(切除受累肠段并保留“受害者”肠段)。对59例因克罗恩病接受手术且有80个肠-肠瘘的患者进行了回顾性研究。
主要手术指征为有症状的肠道狭窄(56%)或经药物治疗无效的腹部肿块(20%)。33例患者(56%)在手术中发现瘘管。39个瘘管(49%)接受了保守治疗。41个瘘管(51%)因瘘管两端靠近或克罗恩病的扩展而采用了根治性治疗。66个瘘管(82.5%)的组织学检查显示,克罗恩病仅累及一段肠管,另一段仅表现为非特异性特征;其余14个瘘管(17.5%)中,克罗恩病累及两段肠管。
肠-肠瘘的临床表现(非特异性症状、术中诊断常见)及其病理特征(“受害者”肠段常无克罗恩病)支持采用保守性手术方法,即适应于克罗恩病实际累及的肠管情况。