鸡心脏形态发生蛋白ES/130的人类后代。

A human descendant of the chicken cardiac morphogenic protein ES/130.

作者信息

Print C G, Krissansen G W

机构信息

Department of Molecular Medicine, University of Auckland, New Zealand.

出版信息

Gene. 1995 Feb 14;153(2):293-4. doi: 10.1016/0378-1119(95)00702-8.

DOI:10.1016/0378-1119(95)00702-8

PMID:7875609

Abstract

We report a striking amino-acid sequence similarity between a chicken extracellular matrix protein termed ES/130, involved in early cardiac morphogenesis [Rezaee et al., J. Biol. Chem. 268 (1993) 14404-14411], and a novel human protein termed CG-1, isolated from the glycoprotein fraction of peripheral blood leukocytes [Print et al., Gene 144 (1994) 221-228]. These two proteins may be homologues which have evolved over a period of 270 x 10(6) years.

摘要

我们报道了一种参与早期心脏形态发生的鸡细胞外基质蛋白ES/130[Rezaee等人，《生物化学杂志》268(1993)14404 - 14411]与一种从外周血白细胞糖蛋白组分中分离出的新型人类蛋白CG-1之间显著的氨基酸序列相似性。这两种蛋白可能是在270×10⁶年的时间里进化而来的同源物。