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A novel cytochrome P-450IID6 (CYPIID6) mutant gene associated with multiple system atrophy.

作者信息

Iwahashi K, Miyatake R, Tsuneoka Y, Matsuo Y, Ichikawa Y, Hosokawa K, Sato K, Hayabara T

出版信息

J Neurol Neurosurg Psychiatry. 1995 Feb;58(2):263-4. doi: 10.1136/jnnp.58.2.263.

DOI:10.1136/jnnp.58.2.263
PMID:7876880
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1073346/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6d0/1073346/2dcb0d0814c1/jnnpsyc00026-0136-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6d0/1073346/2dcb0d0814c1/jnnpsyc00026-0136-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6d0/1073346/2dcb0d0814c1/jnnpsyc00026-0136-a.jpg

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引用本文的文献

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Genetic players in multiple system atrophy: unfolding the nature of the beast.多种系统萎缩中的遗传因素：揭示疾病本质。
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Quantitative PCR-based screening of alpha-synuclein multiplication in multiple system atrophy.基于定量PCR的多系统萎缩中α-突触核蛋白倍增的筛查

本文引用的文献

1
Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine.帕金森病的生态遗传学：异喹胍的4-羟化作用。
Lancet. 1985 Nov 30;2(8466):1213-6. doi: 10.1016/s0140-6736(85)90743-3.
2
Multiple system atrophy--the nature of the beast.多系统萎缩——疾病的本质
J Neurol Neurosurg Psychiatry. 1989 Jun;Suppl(Suppl):78-89. doi: 10.1136/jnnp.52.suppl.78.
3
Metabolism and brain accumulation of tetrahydroisoquinoline (TIQ) a possible parkinsonism inducing substance, in an animal model of a poor debrisoquine metabolizer.
Parkinsonism Relat Disord. 2007 Aug;13(6):340-2. doi: 10.1016/j.parkreldis.2006.12.005. Epub 2007 Feb 8.
4
Epidemiological evidence on multiple system atrophy.多系统萎缩的流行病学证据。
J Neural Transm (Vienna). 2005 Dec;112(12):1605-12. doi: 10.1007/s00702-005-0380-7.
5
Multiple system atrophy: cellular and molecular pathology.多系统萎缩：细胞与分子病理学
Mol Pathol. 2001 Dec;54(6):419-26.
6
Arg296 to Cys296 polymorphism in exon 6 of cytochrome P-450-2D6 (CYP2D6) is not associated with multiple system atrophy.细胞色素P-450-2D6（CYP2D6）第6外显子中从精氨酸296到半胱氨酸296的多态性与多系统萎缩无关。
J Neurol Neurosurg Psychiatry. 1995 Nov;59(5):557. doi: 10.1136/jnnp.59.5.557.
在异喹胍代谢不良动物模型中，四氢异喹啉（TIQ，一种可能诱发帕金森症的物质）的代谢及脑内蓄积情况
Life Sci. 1990;46(8):599-605. doi: 10.1016/0024-3205(90)90128-e.
4
Parkinsonism in monkeys produced by chronic administration of an endogenous substance of the brain, tetrahydroisoquinoline: the behavioral and biochemical changes.通过长期给予大脑内源性物质四氢异喹啉诱导的猴子帕金森症：行为和生化变化
Neurosci Lett. 1990 Oct 30;119(1):109-13. doi: 10.1016/0304-3940(90)90768-5.
5
Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease.异喹胍羟化酶基因多态性与帕金森病易感性
Lancet. 1992 Jun 6;339(8806):1375-7. doi: 10.1016/0140-6736(92)91196-f.
6
Mutant debrisoquine hydroxylation genes in Parkinson's disease.
Lancet. 1992 Apr 25;339(8800):1017-8. doi: 10.1016/0140-6736(92)90537-d.