Hertz D E, Denne S C, Liechty E A
Department of Pediatrics, Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis.
J Perinatol. 1994 Nov-Dec;14(6):446-9.
This study was undertaken to assess the incidence of culture-proved sepsis in term infants without symptoms born to mothers receiving intrapartum antibiotics and to determine the usefulness of the immature neutrophil: total neutrophil (I:T) ratio in the initial evaluation of these infants. A retrospective chart review was made of 103 infants born during a 3-year period. There was one positive blood culture and two positive cerebrospinal fluid cultures in three different patients; all three isolates were considered contaminants and all patients remained without symptoms. In spite of the lack of culture-proved sepsis and clinical illness, more than 50% of the initial I:T ratios were greater than the usually accepted upper limit of normal (that is, 0.16). We conclude that the incidence of sepsis in this population is very low and the initial I:T ratio is not useful as a predictive tool in term newborns without symptoms.
本研究旨在评估接受产时抗生素治疗的母亲所生无症状足月儿中经培养证实的败血症发病率，并确定未成熟中性粒细胞与总中性粒细胞（I:T）比值在这些婴儿初始评估中的作用。对3年期间出生的103例婴儿进行了回顾性病历审查。在3例不同患者中，有1例血培养阳性和2例脑脊液培养阳性；所有3株分离菌均被视为污染物，所有患者均无症状。尽管缺乏经培养证实的败血症和临床疾病，但超过50%的初始I:T比值高于通常公认的正常上限（即0.16）。我们得出结论，该人群中败血症的发病率非常低，初始I:T比值作为无症状足月儿的预测工具并无用处。
