Doyle K J, Luxford W M
University of California Irvine, Orange.
Laryngoscope. 1995 Mar;105(3 Pt 1):263-7. doi: 10.1288/00005537-199503000-00008.
From 1978 to 1993, 59 patients (60 ears) with congenital middle ear cholesteatoma were treated at the House Ear Clinic. The median patient age at presentation was 5 years, and the period of postoperative follow-up was 4.8 years. An intact canal wall was maintained in 58 of 60 cases and a closed middle ear space in all cases. In 12 operations, lateral graft tympanoplasty eradicated the cholesteatoma in one stage; 32 patients required a second-stage surgery to rule out recurrence, and the remaining 16 cases required three or more operations to eradicate disease and reconstruct the hearing mechanism. Thirty-five (63%) of 56 patients had a postoperative air-conduction threshold pure-tone average (PTA) within 10 dB of the best bone-conduction PTA; 91% were within 20 dB. Average speech reception threshold improved from 32 dB hearing level (HL) preoperatively to 20 dB HL postoperatively.
1978年至1993年期间，豪斯耳科诊所共治疗了59例（60耳）先天性中耳胆脂瘤患者。患者就诊时的中位年龄为5岁，术后随访时间为4.8年。60例中有58例保留了完整的外耳道壁，所有病例中耳腔均封闭。在12例手术中，外置植片鼓室成形术一期根除了胆脂瘤；32例患者需要二期手术以排除复发，其余16例患者需要三次或更多次手术来根除疾病并重建听力机制。56例患者中有35例（63%）术后气导阈值纯音平均听阈（PTA）比最佳骨导PTA低10dB以内；91%在20dB以内。平均言语接受阈从术前的32dB听力级（HL）提高到术后的20dB HL。
