Okumura T, Takahashi H, Honjo I, Takagi A, Mitamura K
Department of Otolaryngology, Otsu Red Cross Hospital, Nagara, Japan.
Laryngoscope. 1995 Mar;105(3 Pt 1):289-93; discussion 293-4. doi: 10.1288/00005537-199503000-00012.
In examining 181 patients (327 ears) with sensorineural hearing loss of unknown etiology and 25 people (50 ears) with normal hearing by high-resolution computed tomography (CT), the image of the large vestibular aqueduct (VA) was defined as being a visible large aperture (> or = 4 mm), and small distance between vestibule and traceable part of the VA nearest to the vestibule (> or = 1 mm). The large VA was found in 13 patients (23 ears, 7.0%); it was relatively frequent following hypoplastic cochlea (33 ears, 10.1%) in all the inner ear anomalies detected. In patients with large VA, high-frequency hearing was affected more than low frequency, and history of sudden hearing loss was observed frequently (61% of ears with large VA), which was found to be triggered by characteristic episodes such as minor head trauma, etc. Those clinical features were observed more in those without cochlear anomaly than in those accompanying cochlear anomaly. Pathogenesis of sensorineural hearing loss and characteristic fluctuation of hearing in those patients are discussed.
通过高分辨率计算机断层扫描（CT）对181例病因不明的感音神经性听力损失患者（327耳）和25例听力正常者（50耳）进行检查，大前庭导水管（VA）的影像定义为可见的大孔径（≥4mm），以及前庭与最靠近前庭的VA可追踪部分之间的小距离（≥1mm）。在13例患者（23耳，7.0%）中发现了大VA；在所有检测到的内耳异常中，大VA在耳蜗发育不全（33耳，10.1%）后相对常见。在大VA患者中，高频听力比低频听力受影响更大，并且经常观察到突然听力损失的病史（大VA耳的61%），发现其由轻微头部外伤等特征性事件引发。这些临床特征在无耳蜗异常的患者中比在伴有耳蜗异常的患者中观察到的更多。讨论了这些患者感音神经性听力损失的发病机制和听力的特征性波动。
