Gignoux M, Valla A, Launoy G, Herbert C
Centre Hospitalier Universitaire Côte de Nacre, Caen.
Rev Prat. 1994 Dec 15;44(20):2700-5.
Despite numerous publications on the subject, the debate over the merits of the various methods available for screening for colorectal cancer is continuing. Choice of the method depends on the patient being treated. In the present state of our knowledge, mass screening by Hemoccult, which is of low cost but of poor sensitivity and only fairly well accepted, cannot be used routinely but must be further evaluated and developed. In persons willing to undergo regular examinations, an annual or biannual Hemoccult examination associated with rectosigmoidoscopy every 5 years appears appropriate. In subjects having a familial history in first-degree relatives, colonoscopic examination every 5 years is adequate. Lastly, in patients with a personal history of cancer or adenoma, screening consists of colonoscopic follow-up adapted to the individual case.
尽管关于该主题已有大量出版物，但针对各种可用的结直肠癌筛查方法的优缺点的争论仍在继续。方法的选择取决于所治疗的患者。就我们目前的知识水平而言，潜血检查进行大规模筛查成本低但灵敏度差且仅得到一定程度的认可，不能常规使用，而必须进一步评估和改进。对于愿意接受定期检查的人，每年或每两年进行一次潜血检查并每5年进行一次乙状结肠镜检查似乎是合适的。对于有一级亲属家族病史的受试者，每5年进行一次结肠镜检查就足够了。最后，对于有个人癌症或腺瘤病史的患者，筛查包括根据个体情况进行结肠镜随访。
