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一家儿童诊所链球菌性咽喉炎的微生物学与流行病学研究:一项为期一年的研究。

Microbiological and epidemiological study of streptococcal sore throat at a children's clinic: a one-year study.

作者信息

Gharagozloo R, Jamshidi M S, Ghadimi H

出版信息

Pahlavi Med J. 1976 Jul;7(3):334-43.

PMID:787894
Abstract

From October 1973 to September 1974, throat cultures were taken from 578 patients who referred to the Children's Clinic with upper respiratory tract infection. One hundred fifty-one (26%) of the sick children yielded beta-hemolytic streptococci and 427 (74%) of the pharyngitis cases were considered as viral. The most susceptible ages for streptococcal and viral pharyngitis were 5-8 and 2-6 years respectively. The peak seasonal incidence for streptococcal sore throat was from late autumn to early spring. There was a positive correlation between the incidence of upper respiratory infection and streptococcal isolation. From 100 strains of beta-hemolytic streptococci isolated and tested, 86 were group "A", 4 group "C", 2 group "G" and 8 non-groupable. From 86 group "A" strains. 71 (82%) were typable by agglutination ("T"-typing), but only 49 (57%) by precipitation ("M"-typing). The most prevalent "M" types were types 1 and 12. There was 95% correlation between serological and bacitracin disk method for grouping of hemolytic streptococci. All strains isolated were sensitive to penicillin, erythromycin and chloramphenicol, but 11 strains were resistant to tetracyclin.

摘要

1973年10月至1974年9月,从578名因上呼吸道感染到儿童诊所就诊的患者中采集了咽喉培养物。151名(26%)患病儿童培养出β溶血性链球菌,427例(74%)咽炎病例被认为是病毒性的。链球菌性咽炎和病毒性咽炎最易感的年龄分别为5至8岁和2至6岁。链球菌性咽痛的季节性发病高峰是从深秋到早春。上呼吸道感染的发病率与链球菌分离之间存在正相关。在分离并检测的100株β溶血性链球菌中,86株为A组,4株为C组,2株为G组,8株不可分组。在86株A组菌株中,71株(82%)可通过凝集反应分型(“T”分型),但只有49株(57%)可通过沉淀反应分型(“M”分型)。最常见的“M”型是1型和12型。溶血性链球菌分组的血清学方法和杆菌肽纸片法之间有95%的相关性。所有分离出的菌株对青霉素、红霉素和氯霉素敏感,但有11株对四环素耐药。

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