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Rapamycin abrogates accelerated rejection in sensitized rats by selectively suppressing intragraft cell activation, adhesion/binding properties, and modulating serum alloantibody responses.

作者信息

Schmidbauer G, Hancock W W, Wasowska B, Binder J, Padberg W, Kupiec-Weglinski J W

机构信息

Department of Surgery, Justus Liebig University, Giessen, Germany.

出版信息

Transplant Proc. 1995 Feb;27(1):427-9.

PMID:7879048
Abstract
摘要

相似文献

1
Rapamycin abrogates accelerated rejection in sensitized rats by selectively suppressing intragraft cell activation, adhesion/binding properties, and modulating serum alloantibody responses.
Transplant Proc. 1995 Feb;27(1):427-9.
2
Cytokine and alloantibody networks in long-term cardiac allografts in rapamycin-treated sensitized rat recipients.雷帕霉素治疗的致敏大鼠心脏移植受者长期心脏同种异体移植中的细胞因子和同种异体抗体网络
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3
Rapamycin treatment prevents and/or erases sensitization and abrogates accelerated rejection of vascularized organ allografts.
Transplant Proc. 1993 Feb;25(1 Pt 1):712-3.
4
Abrogation by rapamycin of accelerated rejection in sensitized rats by inhibition of alloantibody responses and selective suppression of intragraft mononuclear and endothelial cell activation, cytokine production, and cell adhesion.雷帕霉素通过抑制同种抗体反应以及选择性抑制移植内单核细胞和内皮细胞活化、细胞因子产生和细胞黏附,从而消除致敏大鼠的加速排斥反应。
Transplantation. 1994 Mar 27;57(6):933-41. doi: 10.1097/00007890-199403270-00028.
5
Cytokine and alloantibody networks in long term cardiac allografts in rat recipients treated with rapamycin.用雷帕霉素治疗的大鼠心脏移植受者长期心脏同种异体移植物中的细胞因子和同种异体抗体网络
J Immunol. 1996 Jan 1;156(1):395-404.
6
Rapamycin reverses acute heart, kidney, and pancreas allograft rejection and prevents accelerated heart allograft rejection in the rat.雷帕霉素可逆转大鼠急性心脏、肾脏和胰腺移植排斥反应,并预防心脏移植加速性排斥反应。
Transplant Proc. 1993 Feb;25(1 Pt 1):719-20.
7
Donor pretreatment with methylprednisolone synergistically prolongs survival of cardiac allografts in sensitized rat recipients conditioned with rapamycin.用甲泼尼龙对供体进行预处理可协同延长经雷帕霉素预处理的致敏大鼠受体心脏同种异体移植物的存活时间。
Transplant Proc. 1997 Feb-Mar;29(1-2):607-8. doi: 10.1016/s0041-1345(96)00322-3.
8
Rapamycin's long-term effects on humoral and cellular immune responses in the rat.
Transplant Proc. 1993 Feb;25(1 Pt 1):721-2.
9
Efficacy and mechanism of action of rapamycin in presensitized recipients of experimental allografts.雷帕霉素在实验性同种异体移植预致敏受者中的疗效及作用机制
Transplant Proc. 1992 Oct;24(5):1669-70.
10
Leflunomide abrogates accelerated heart allograft rejection in presensitized rats.来氟米特可消除预致敏大鼠中加速的心脏同种异体移植排斥反应。
Transplant Proc. 1997 Feb-Mar;29(1-2):1294-5. doi: 10.1016/s0041-1345(96)00524-6.