TNF-alpha upregulates the expression of fibronectin in acutely rejecting rat cardiac allografts. - Suppr | 超能文献

TNF-alpha upregulates the expression of fibronectin in acutely rejecting rat cardiac allografts.

作者信息

Coito A J, Binder J, Brown L F, de Sousa M, Van de Water L, Kupiec-Weglinski J W

机构信息

Harvard Medical School, Department of Surgery, Brigham and Women's Hospital, Boston, MA 02115.

出版信息

Transplant Proc. 1995 Feb;27(1):463-5.

Abstract

摘要

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TNF-alpha upregulates the expression of fibronectin in acutely rejecting rat cardiac allografts.

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TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway.转化生长因子-β通过一条依赖c-Jun氨基末端激酶、不依赖Smad4的途径诱导纤连蛋白的合成。

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