Biddle C
AANA J. 1994 Dec;62(6):537-43; quiz 544.
Many breast-feeding women are exposed to anesthetic drugs. The question of breast feeding following an anesthetic is a highly relevant issue in part because it is desirable to allow breast feeding to resume quickly while minimizing the potential for drug-related infant morbidity. The physiology of breast milk production and the factors influencing the transfer of drugs into breast milk is reviewed. Generally there is incomplete or sparse information on the potential effects upon the suckling infant. Despite this, certain reasonable conclusions and recommendations can be developed. Among these include a substantive risk with high-dose and long-standing therapies, particular vulnerability in the premature neonate or when a mother is receiving multidose therapy, and consideration of temporarily interrupting the feeding schedule where sufficient doubt exists. Overall, the importance of breast feeding must be carefully considered in light of the potential for side effects in each maternal/child scenario.
许多哺乳期妇女会接触到麻醉药物。麻醉后母乳喂养的问题是一个高度相关的问题,部分原因是希望在尽量减少药物相关婴儿发病风险的同时,尽快恢复母乳喂养。本文综述了母乳产生的生理学以及影响药物进入母乳的因素。一般来说,关于对哺乳婴儿潜在影响的信息不完整或稀少。尽管如此,仍可得出某些合理的结论并提出建议。其中包括高剂量和长期治疗存在重大风险,早产儿或母亲接受多剂量治疗时特别脆弱,以及在存在足够疑问的情况下考虑暂时中断喂养计划。总体而言,鉴于每种母婴情况中副作用的可能性,必须仔细考虑母乳喂养的重要性。