Kawahara M
Dept. of Internal Medicine, National for Chest Disease, Kinki Central Hospital.
Gan To Kagaku Ryoho. 1995 Feb;22(3):335-40.
Large phase III studies for lung cancer are reviewed. In an effort to improve survival results in locally advanced inoperable non-small-cell lung cancer (NSCLC), several studies have documented survival advantage for cisplatin + vinka alkaloid followed by radiotherapy (RT) when compared with RT alone. In SCLC, meta-analyses show that thoracic radiotherapy moderately improves survival in patients who are treated with combination chemotherapy. The optimum combination of chemotherapy and radiotherapy needs to be established.
本文综述了针对肺癌的大型III期研究。为了提高局部晚期不可切除非小细胞肺癌（NSCLC）的生存结果，多项研究表明，与单纯放疗相比，顺铂+长春花生物碱联合放疗后患者的生存具有优势。在小细胞肺癌（SCLC）中，荟萃分析表明，胸部放疗可适度提高接受联合化疗患者的生存率。化疗和放疗的最佳组合仍有待确定。
