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锝-99m六甲基丙二胺肟脑单光子发射计算机断层扫描与难治性癫痫半球切除术的结果

Technetium-99m HmPAO brain SPECT and outcome of hemispherectomy for intractable seizures.

作者信息

Carmant L, O'Tuama L A, Roach P J, Kramer U, Mikati M A, Riviello J J, Helmers S L, Madsen J R, Black P M, Lombroso C T

机构信息

Department of Neurology, Children's Hospital; Harvard Medical School, Boston, Massachusetts 02115.

出版信息

Pediatr Neurol. 1994 Oct;11(3):203-7. doi: 10.1016/0887-8994(94)90103-1.

DOI:10.1016/0887-8994(94)90103-1
PMID:7880333
Abstract

With recent descriptions of the modified hemispherectomies and hemicorticectomy, there has been renewed interest in hemispherectomy for treatment of intractable seizures with hemiparesis. Because long-term outcome remains uncertain, patient selection remains difficult. 99mTc-HmPAO brain SPECT has been a helpful adjunct in the evaluation of epilepsy surgery candidates. We report SPECT scan findings in 7 patients who underwent hemispherectomy and compare these results with scalp EEG findings. Six patients had unilateral SPECT findings and all had a favorable outcome, regardless of surface EEG findings.

摘要

随着最近对改良半球切除术和大脑半球皮质切除术的描述,人们对采用半球切除术治疗伴有偏瘫的顽固性癫痫重新产生了兴趣。由于长期疗效仍不确定,患者的选择仍然困难。99mTc-HmPAO脑单光子发射计算机断层扫描(SPECT)在评估癫痫手术候选者方面一直是一种有用的辅助手段。我们报告了7例接受半球切除术患者的SPECT扫描结果,并将这些结果与头皮脑电图结果进行比较。6例患者有单侧SPECT表现,无论头皮脑电图结果如何,所有患者均获得了良好的疗效。

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