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血液样本在制备和储存过程中的同源物产生。

Congener production in blood samples during preparation and storage.

作者信息

Felby S, Nielsen E

机构信息

Forensic Chemistry Dept. University of Copenhagen, Denmark.

出版信息

Blutalkohol. 1995 Jan;32(1):50-8.

PMID:7880489
Abstract

The possibility of congener production in blood during storage was studied. The material consisted of 216 blood specimens in which ethanol was not detected. We divided the specimens into two groups, A and B. Group A: 97 specimens were stored at 4 degrees C until alcohol analysis, and only exposed shortly to room temperature during the aseptic preparation for analysis. Group B: 119 specimens were stored at 17 degrees C until alcohol analysis were performed, and the handling during preparation was not aseptic. All specimens were subsequently stored at 4 degrees C. After three to twelve months of storage the blood specimens were analyzed for congeners. None of the forensic important congeners (n-propanol, isobutanol, or butanol-2) were detected in Group A, whereas in Group B n-propanol was detected in fourteen of the specimens, isobutanol in sixteen, and butanol-2 in two specimens.

摘要

研究了血液在储存过程中产生同系物的可能性。材料包括216份未检测到乙醇的血液标本。我们将标本分为A、B两组。A组:97份标本在4℃下储存直至进行酒精分析,并且在无菌分析准备过程中仅短时间暴露于室温。B组:119份标本在17℃下储存直至进行酒精分析,并且准备过程中的操作并非无菌。所有标本随后均在4℃下储存。储存三至十二个月后,对血液标本进行同系物分析。A组未检测到任何具有法医重要性的同系物(正丙醇、异丁醇或2-丁醇),而B组在14份标本中检测到正丙醇,16份中检测到异丁醇,2份标本中检测到2-丁醇。

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引用本文的文献

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Molecules. 2022 Jan 21;27(3):700. doi: 10.3390/molecules27030700.
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Alcohol congener analysis and the source of alcohol: a review.酒精同系物分析与酒精来源:综述
Forensic Sci Med Pathol. 2013 Jun;9(2):194-207. doi: 10.1007/s12024-013-9411-0. Epub 2013 Mar 3.