Ambrus C M, Choi T S, Cunnanan E, Eisenberg B, Staub H P
Res Commun Chem Pathol Pharmacol. 1976 Sep;15(1):195-8.
Five hundred premature infants were treated in a double blind, randomized study with intravenous plasminogen or placebo within 60 minutes of birth. There was a significant decrease in severe clinical respiratory distress, death due to hyaline membrane disease and total mortality in the plasminogen treated infants as compared to the controls.
在一项双盲随机研究中,500名早产儿在出生后60分钟内接受了静脉注射纤溶酶原或安慰剂治疗。与对照组相比,接受纤溶酶原治疗的婴儿严重临床呼吸窘迫、因透明膜病导致的死亡以及总死亡率均显著降低。