Gábriel R, Straznicky C
Department of Zoology, Janus Pannonius University, Pécs, Hungary.
Neurobiology (Bp). 1994;2(3):235-43.
Horseradish peroxidase was applied to the proximal stump of the cut optic nerve, and the anterogradely transported tracer was visualised by the cobalt-intensified diaminobenzidine method. The optic fibre receiving laminae of the optic tectum were systematically searched for those synapses in which the tracer-filled profiles occupied postsynaptic positions. Optic terminals were rarely but regularly postsynaptic to unlabelled, small clear vesicle-containing profiles, mostly in lamina A. Quantitative analysis showed that only in 0.95% of the synapses formed by optic fibres could this arrangement be substantiated. These results suggest that presynaptic modulatory mechanisms may play a role in optic information processing.
将辣根过氧化物酶应用于切断的视神经近端残端，并通过钴增强二氨基联苯胺法观察顺行运输的示踪剂。对视顶盖的视神经纤维接受层进行系统搜索，寻找那些示踪剂填充的轮廓占据突触后位置的突触。视神经终末很少但有规律地作为未标记的、含有小清亮囊泡的轮廓的突触后成分，主要位于A层。定量分析表明，仅在由视神经纤维形成的突触中，有0.95%的突触符合这种情况。这些结果表明，突触前调节机制可能在视觉信息处理中起作用。
