De Guevara R, Pairault C, Pinganaud G
Université Paris VII, équipe de Neuroembryologie, France.
C R Acad Sci III. 1994 Aug;317(8):737-41.
The glial cell development was studied during the edification of the retina and the optic tract, in a teleost, the rainbow trout. The intermediate filament proteins, vimentin and glial fibrillary acidic protein (GFAP) were visualized by an indirect immunohistochemical method. Results show that both vimentin and GFAP are early expressed in the developing retina and, particularly in the Müller cells, a coexpression of vimentin and GFAP is observed from embryonic to adult stages. The ganglion cell layer and the optic fiber layer both exhibit GFAP-positive structures. The deep staining for GFAP is also seen in the optic nerve and induces us to credit astrocyte-like cells with a leading role in the pattern formation of this tract.
在硬骨鱼虹鳟鱼视网膜和视束形成过程中，对神经胶质细胞发育进行了研究。通过间接免疫组织化学方法观察中间丝蛋白波形蛋白和胶质纤维酸性蛋白（GFAP）。结果表明，波形蛋白和GFAP在发育中的视网膜中均早期表达，特别是在米勒细胞中，从胚胎期到成年期均观察到波形蛋白和GFAP的共表达。神经节细胞层和视神经纤维层均显示GFAP阳性结构。在视神经中也可见GFAP的深染，这使我们认为星形胶质细胞样细胞在该神经束的模式形成中起主导作用。
