Pateisky K, Wessely P
Wien Klin Wochenschr. 1976 Mar 5;88(5):153-7.
A review is given of the present state of knowledge and current concepts of the causative factors involved in, and the pathological mechanisms underlying status epilepticus. A synopsis of the commonly-applied therapeutic methods is presented. A step-wise therapeutic procedure is advised for the different stages of status epilepticus. Treatment is directed towards a lowering of cerebral excitability (hydantoin, diazepam), the prevention of brain oedema (osmotherapy, positive pressure respiration) and the avoidance of the development of secondary complications (antibiotics, intensive care). In every case the requisite investigations should be undertaken in order to clarify the aetiology.
本文综述了癫痫持续状态相关致病因素及病理机制的现有知识和当前概念。介绍了常用治疗方法的概要。针对癫痫持续状态的不同阶段,建议采用逐步治疗程序。治疗旨在降低大脑兴奋性(使用苯妥英、地西泮)、预防脑水肿(采用渗透性疗法、正压通气)以及避免继发并发症的发生(使用抗生素、加强护理)。在每种情况下,都应进行必要的检查以明确病因。