Petrelli G, Menniti Ippolito F, Spila Alegiani S, Magarotto G, Taroni F
Department of Epidemiology and Biostatistics, Istituto Superiore di Sanità, Rome, Italy.
Med Lav. 1994 Sep-Oct;85(5):397-401.
During the last ten years, interest has been focussed on occupational exposure in thermoelectric power plants (i.e., coal dust, polycyclic aromatic hydrocarbons, dioxin, dielectric liquids, PCB's, asbestos, etc.), although available evidence on its effects on the health status of the occupational population are far from being definitive. A retrospective cohort study was carried out to investigate the association between exposure to risk factors and mortality for cancer in three thermoelectric power plants located in the north-east of Italy. The three plants studied started with oil and coal but since 1968 they utilized mostly coal as fuel. In spite of the different fuel used at the beginning, the production process has been fairly constant since the main conversion from oil to coal with a substantial increase in power production. A total of 1,772 male workers were included in the total study cohort and followed-up from 1968 to 1987, with a total of 22,090 person-years of exposure. Eighty percent of the cohort began to work in the plant before 30 years of age, and had a mean period of employment of 9.5 years. The cohort was completely traced to the end of the follow-up period by using an original computer system based on personal fiscal codes. Causes of death were ascertained in the municipalities where the deaths occurred and coded according to the International Classification of Disease, IX Revision. During the study period 68 deaths were observed with an SMR for all causes of death equal to 0.79.(ABSTRACT TRUNCATED AT 250 WORDS)
在过去十年中,人们的关注点集中在热电厂的职业暴露(如煤尘、多环芳烃、二噁英、绝缘液体、多氯联苯、石棉等)上,尽管现有证据表明其对职业人群健康状况的影响远未明确。开展了一项回顾性队列研究,以调查意大利东北部三座热电厂中接触风险因素与癌症死亡率之间的关联。所研究的这三座工厂最初使用石油和煤炭,但自1968年以来主要使用煤炭作为燃料。尽管一开始使用的燃料不同,但自主要从石油转换为煤炭以来,生产过程相当稳定,发电量大幅增加。总研究队列共纳入1772名男性工人,从1968年至1987年进行随访,总暴露人年数为22090人年。该队列中80%的人在30岁之前开始在工厂工作,平均就业时长为9.5年。通过使用基于个人财政代码的原始计算机系统,该队列在随访期结束时被完全追踪。死亡原因在死亡发生的市政当局确定,并根据《国际疾病分类》第九版进行编码。在研究期间,观察到68例死亡,所有死因的标准化死亡比为0.79。(摘要截短于250字)