Rey G J, Tomer R, Levin B E, Sanchez-Ramos J, Bowen B, Bruce J H
Department of Neurology, University of Miami, Florida 33136.
Mov Disord. 1995 Jan;10(1):106-10. doi: 10.1002/mds.870100117.
We longitudinally examined the neuropsychological and psychiatric characteristics of an adult male with pathologically confirmed corticobasal ganglionic degeneration (CBGD). The patient was seen on an inpatient and outpatient basis by members of the Departments of Neurology and Radiology of the University of Miami School of Medicine. Longitudinal neuropsychological testing revealed a lateralized cortical-subcortical dementia and left visual field inattention consistent with neurological and postmortem neuropathological findings of greater right hemisphere dysfunction. Symptoms of depression and obsessive-compulsive symptomatology were also documented. Our findings are consistent with prior reports indicating that CBGD is characterized by lateralized cerebral dysfunction and suggest that a detailed neuropsychological examination is a useful procedure to assist in the differential diagnosis of this movement disorder.
我们对一名经病理证实患有皮质基底节变性（CBGD）的成年男性的神经心理学和精神特征进行了纵向研究。迈阿密大学医学院神经科和放射科的成员对该患者进行了住院和门诊检查。纵向神经心理学测试显示出一种偏侧化的皮质 - 皮质下痴呆以及左侧视野疏忽，这与右侧半球功能障碍更严重的神经学和死后神经病理学发现一致。还记录了抑郁症状和强迫症状。我们的研究结果与先前的报告一致，表明CBGD的特征是偏侧化的脑功能障碍，并表明详细的神经心理学检查是有助于该运动障碍鉴别诊断的有用程序。
