半侧巨脑症中的代谢减低与偶极子定位：一例报告

Hypometabolism and dipole localization in hemimegalencephaly: a case report.

作者信息

Ohta Y, Hiraiwa M, Murayama K, Nonaka-Mishima M, Kaneko Y, Yumoto M, Yotsumoto H, Iio M

机构信息

Department of Pediatrics, Teikyo University School of Medicine, Japan.

出版信息

Neuropediatrics. 1994 Oct;25(5):255-8. doi: 10.1055/s-2008-1073031.

DOI:10.1055/s-2008-1073031

PMID:7885535

Abstract

A case of hemimegalencephaly was studied by means of neuroimaging (CT, MRI and PET) and magnetoencephalography (MEG). Hemimegalencephaly (HM) is a neuronal migration disorder. This is the first report of evaluation of HM with the use of PET and MEG from not only the morphological but also the functional point of view. PET with 11C-glucose showed a low radioactive concentration in the affected hemisphere, which suggested a metabolic deficit. MEG proved the epileptic foci existed mainly in the affected hemisphere, especially around a heterotopia and the pachygyric cortex, which was disclosed on MRI.

摘要

通过神经影像学（CT、MRI和PET）以及脑磁图（MEG）对一例半侧巨脑症病例进行了研究。半侧巨脑症（HM）是一种神经元迁移障碍疾病。这是首例不仅从形态学角度，而且从功能角度使用PET和MEG对半侧巨脑症进行评估的报告。11C-葡萄糖PET显示患侧半球放射性浓度较低，提示代谢缺陷。MEG证实癫痫病灶主要存在于患侧半球，尤其是在MRI显示的异位灶和巨脑回皮质周围。