Boudéne C, Boisset M
Ann Biol Clin (Paris). 1976;34(1):1-40.
The authors emphasize the influence of hormonal and nutritional factors on the activity level of microsomal enzymes. Induction process of hepatic cytochrome P450 and microsomal enzymes by xenobiotics are described. The existence of different types of hemoprotein P450 in response to the action of different inductors is discussed. We also propose some hypothesis concerning the action mechanism of inhibitors of microsomal enzymes and we point out the role of environmental pollutants.
作者强调了激素和营养因素对微粒体酶活性水平的影响。描述了异生素对肝细胞色素P450和微粒体酶的诱导过程。讨论了不同类型的血红蛋白P450在不同诱导剂作用下的存在情况。我们还提出了一些关于微粒体酶抑制剂作用机制的假说，并指出了环境污染物的作用。
