Goudemand J, Anssens R, Delmas-Marsalet Y, Farriaux J P, Fontaine G
Arch Fr Pediatr. 1976 Feb;33(2):121-9.
A bone marrow graft was performed in a 3 1/2 year old boy suffering from chronic granulomatous disease. Donor-recipient matching was complete in the ABO, HL-A and M.L.C. systems. The number of injected cells amounted to 5.4 X 10(9) (3.6 X 10(8) cells/kg body weight). The immunosuppression regimen consisted of cyclophosphamide and A.L.S. before the graft, and methotrexate after it. Neither graft versus host reaction, nor secondary infection developed. The take of the graft was monitored by the Gm allotypes. Rejection, however, occurred after 2 months.
对一名患有慢性肉芽肿病的3岁半男孩进行了骨髓移植。供受者在ABO、HL - A和混合淋巴细胞培养（M.L.C.）系统中完全匹配。注入的细胞数量为5.4×10⁹（3.6×10⁸个细胞/千克体重）。免疫抑制方案在移植前包括环磷酰胺和抗淋巴细胞血清（A.L.S.），移植后使用甲氨蝶呤。既未发生移植物抗宿主反应，也未出现继发感染。通过Gm同种异型监测移植物的存活情况。然而，2个月后发生了排斥反应。
