'Unilateral cone dystrophy': ERG changes implicate abnormal signaling by hyperpolarizing bipolar and/or horizontal cells.
作者信息
Sieving P A
机构信息
W.K. Kellogg Eye Center, Department of Ophthalmology, University of Michigan, Ann Arbor.
出版信息
Trans Am Ophthalmol Soc. 1994;92:459-71; discussion 471-4.
Abstract
The two cases described here appear to represent the infrequently reported entity of "unilateral cone (cone-rod) dystrophy." Both cases give the suggestion that daylight vision can be affected by abnormalities in visual signals in the proximal retina, after they leave the cone photoreceptors themselves. The ERG waveform changes in these two cases are consistent with a deficit in signaling by the hyperpolarizing bipolar cells, and the complaint of abnormal color perception in both cases presented here raises the possibility that the OFF-pathway through hyperpolarizing bipolar cells may be important for color processing.
摘要
相似文献
1
'Unilateral cone dystrophy': ERG changes implicate abnormal signaling by hyperpolarizing bipolar and/or horizontal cells.
Trans Am Ophthalmol Soc. 1994;92:459-71; discussion 471-4.
2
Progressive cone dystrophy with deutan genotype and phenotype.
Graefes Arch Clin Exp Ophthalmol. 2006 Feb;244(2):183-91. doi: 10.1007/s00417-005-0022-7. Epub 2005 Aug 5.
3
Cone dystrophy with supernormal rod response is strictly associated with mutations in KCNV2.
Invest Ophthalmol Vis Sci. 2008 Feb;49(2):751-7. doi: 10.1167/iovs.07-0471.
4
[Differential diagnosis of cone dystrophies].
Ophthalmologe. 1994 Dec;91(6):719-29.
5
Novel KCNV2 mutations in cone dystrophy with supernormal rod electroretinogram.
Am J Ophthalmol. 2008 Jun;145(6):1099-106. doi: 10.1016/j.ajo.2008.02.004. Epub 2008 Apr 9.
6
Local cone and rod system function in progressive cone dystrophy.
Invest Ophthalmol Vis Sci. 2002 Jul;43(7):2364-73.
7
Contribution of rod and cone pathways to the dark-adapted electroretinogram (ERG) b-wave following retinal degeneration in RCS rats.
Vision Res. 2004;44(21):2467-74. doi: 10.1016/j.visres.2004.05.020.
8
Rod and cone a-waves in three cases of Bietti crystalline chorioretinal dystrophy.
Am J Ophthalmol. 2001 Sep;132(3):395-402. doi: 10.1016/s0002-9394(01)00963-1.
9
Interactions between rod and L-cone signals in deuteranopes: gains and phases.
Vis Neurosci. 2006 Mar-Apr;23(2):201-7. doi: 10.1017/S095252380623205X.
10
The multifocal pattern electroretinogram (mfPERG) and cone-isolating stimuli.
Vis Neurosci. 2007 Nov-Dec;24(6):805-16. doi: 10.1017/S0952523807070733.
引用本文的文献
1
Two cases of unilateral cone-rod dysfunction presenting in adult females.
Doc Ophthalmol. 2022 Dec;145(3):271-281. doi: 10.1007/s10633-022-09893-9. Epub 2022 Sep 7.
2
Unilateral cone dysfunction with asymmetric maculopathy - Clinical features, multimodal imaging and genetic analysis of a novel phenotype.
Indian J Ophthalmol. 2020 Nov;68(11):2501-2504. doi: 10.4103/ijo.IJO_795_20.
3
Optical coherence tomography findings in unilateral peripheral cone dysfunction syndrome: a case report.
BMC Ophthalmol. 2019 May 16;19(1):111. doi: 10.1186/s12886-019-1121-2.
4
Visual Cone Arrestin 4 Contributes to Visual Function and Cone Health.
Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5407-16. doi: 10.1167/iovs.15-16647.
5
Case of unilateral peripheral cone dysfunction.
Case Rep Ophthalmol. 2012 May;3(2):162-8. doi: 10.1159/000339129. Epub 2012 May 10.
6
A new mutation in the RP1L1 gene in a patient with occult macular dystrophy associated with a depolarizing pattern of focal macular electroretinograms.
Mol Vis. 2012;18:1031-9. Epub 2012 Apr 24.
7
Depolarizing focal macular electroretinogram pattern after photodynamic therapy in a patient with polypoidal choroidal vasculopathy.
Jpn J Ophthalmol. 2010 Sep;54(5):509-11. doi: 10.1007/s10384-010-0854-5. Epub 2010 Nov 5.
8
Unilateral retinitis pigmentosa and cone-rod dystrophy.
Clin Ophthalmol. 2009;3:263-70. doi: 10.2147/opth.s5130. Epub 2009 Jun 2.
9
Assessment of local cone on- and off-pathway function using multifocal ERG technique.
Doc Ophthalmol. 2000;100(2-3):139-54. doi: 10.1023/a:1002779619050.
10
Evidence supportive of a functional discrimination between photopic oscillatory potentials as revealed with cone and rod mediated retinopathies.
Doc Ophthalmol. 1998;95(1):35-54. doi: 10.1023/a:1001784614333.
本文引用的文献
1
Electrophysiological evaluation of the neuro-ophthalmology patient: an algorithm for clinical use.
Semin Ophthalmol. 1992 Mar;7(1):65-78. doi: 10.3109/08820539209065094.
2
The contribution of on-bipolar cells to the electroretinogram of rabbits and monkeys. A study using 2-amino-4-phosphonobutyrate (APB).
Vision Res. 1984;24(12):1841-6. doi: 10.1016/0042-6989(84)90016-6.
3
2-amino-4-phosphonobutyric acid: a new pharmacological tool for retina research.
Science. 1981 Jan 9;211(4478):182-5. doi: 10.1126/science.6255566.
4
Bipolar cells in the mudpuppy retina use an excitatory amino acid neurotransmitter.
Nature. 1983;303(5917):537-8. doi: 10.1038/303537a0.
5
An excitatory amino acid antagonist blocks cone input to sign-conserving second-order retinal neurons.
Science. 1983 Mar 11;219(4589):1230-2. doi: 10.1126/science.6131536.
6
Night blindness revisited: from man to molecules. Proctor lecture.
Invest Ophthalmol Vis Sci. 1982 Nov;23(5):588-609.
7
Congenital stationary nightblindness.
Trans Am Ophthalmol Soc. 1974;72:448-87.
8
Three cone mechanisms in the primate electroretinogram: two with, one without off-center bipolar responses.
Vision Res. 1986;26(2):245-54. doi: 10.1016/0042-6989(86)90019-2.
9
Neuro-ophthalmic presentation of cone dysfunction syndromes in the adult.
J Clin Neuroophthalmol. 1987 Dec;7(4):202-18.
10
Contribution of the retinal ON channels to scotopic and photopic spectral sensitivity.
Vis Neurosci. 1989 Sep;3(3):225-39. doi: 10.1017/s0952523800009986.
Zotero 插件