Rieber A
Abteilung Röntgendiagnostik, Universität Ulm.
Z Gastroenterol. 1994 Nov;32(11):651-3.
Fibrolamellar carcinoma (FL-Ca) is a primary malignant liver tumor at unknown etiology, without cirrhosis and usually without an increase at tumor markers, which occurs mainly in young patients. As it can simulate malignant and benign tumors, particularly FNH, diagnosis is difficult. Ultrasound and angiography show mostly uncharacteristic features. The highest specificity has CT, if calcifications are present, because these calcifications in a tumor similar to FNH are pathognomonic for FL-Ca. In MRI the central scars of FL-Ca and FNH have a different signal intensity in T2-weighted images, so that MRI becomes more and more important in the differential diagnosis to FNH.
纤维板层癌(FL-Ca)是一种病因不明的原发性肝脏恶性肿瘤,无肝硬化,肿瘤标志物通常不升高,主要发生于年轻患者。由于它可类似恶性和良性肿瘤,尤其是肝局灶性结节性增生(FNH),诊断困难。超声和血管造影大多显示无特征性表现。如果存在钙化,CT具有最高的特异性,因为在类似FNH的肿瘤中出现这些钙化是FL-Ca的特征性表现。在磁共振成像(MRI)中,FL-Ca和FNH的中央瘢痕在T2加权图像上具有不同的信号强度,因此MRI在与FNH的鉴别诊断中越来越重要。