Caseiro-Alves F, Zins M, Rahmouni A, Vilgrain V, Menu Y, Mathieu D
Department of Radiology, Hopital Henri Mondor, 94010 Créteil, France.
Radiology. 1996 Mar;198(3):889-92. doi: 10.1148/radiology.198.3.8628888.
To describe calcification in focal nodular hyperplasia (FNH) of the liver, which poses a new problem for the differentiation of FNH from fibrolamellar hepatocellular carcinoma (HCC).
Ultrasound, computed tomography, and magnetic resonance imaging findings of 357 FNH lesions diagnosed in the past 5 years in 295 patients (274 female, 21 male; aged 14-72 years) were retrospectively reviewed with emphasis on intralesional calcification.
Calcifications were seen in five FNH lesions (1.4%) as small, solitary spots located centrally or peripherally within the lesions. Morphologic features of these calcifications were similar to those of calcifications in two of six fibrolamellar HCCs in the same period.
Calcification in FNH is a rare and atypical finding that poses further difficulty for differentiation from fibrolamellar HCC.
描述肝脏局灶性结节性增生(FNH)中的钙化情况,这给FNH与纤维板层型肝细胞癌(HCC)的鉴别带来了新问题。
回顾性分析过去5年中295例患者(274例女性,21例男性;年龄14 - 72岁)诊断出的357个FNH病变的超声、计算机断层扫描和磁共振成像结果,重点关注病变内钙化情况。
在5个FNH病变(1.4%)中可见钙化,表现为位于病变中央或周边的小的孤立斑点。这些钙化的形态特征与同期6个纤维板层型HCC中的2个的钙化相似。
FNH中的钙化是一种罕见且不典型的表现,给与纤维板层型HCC的鉴别带来了进一步困难。