Böhm K, Lorentz F W
Hautklinik (Charité), Medizinische Fakultät, Humboldt-Universität zu Berlin.
Laryngorhinootologie. 1995 Jan;74(1):36-8. doi: 10.1055/s-2007-997683.
5 patients suffering from high-grade sound conduction deafness due to extensive adhesion process on both ears underwent tympanoplasty on one of the ears. The missing tympanic mucosa was replaced by an autologous cell suspension prepared from mucosa of the maxillary sinus. 6-12 months after re-epithelialisation of the tympanic cavity, reconstruction of the ossicular chain was performed using glasionomer cement prostheses (IONOS). 3 patients showed an improvement of hearing after transplantation of the isolated mucosal cells and following replacement of auditory ossicles. One patient had good improvement of hearing already after reconstruction of the tympanic cavity. In one case reobliteration of the tympanic cavity occurred. The clinical results confirm that using mucosal cell suspensions for reepithelisation of an obliterated tympanic cavity is yet another successful step forward in reconstructive surgery of the middle ear.
5例因双耳广泛粘连而患有重度传音性耳聋的患者，其中一只耳朵接受了鼓室成形术。缺失的鼓膜黏膜由取自上颌窦黏膜制备的自体细胞悬液替代。鼓室重新上皮化6 - 12个月后，使用玻璃离子粘固剂假体（IONOS）进行听骨链重建。3例患者在移植分离的黏膜细胞并更换听小骨后听力有所改善。1例患者在鼓室重建后听力就有了明显改善。1例出现鼓室再次闭塞。临床结果证实，使用黏膜细胞悬液使闭塞的鼓室重新上皮化是中耳重建手术又一个成功的进展。
