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古细菌基因组:真细菌形式与真核生物内容

Archaebacterial genomes: eubacterial form and eukaryotic content.

作者信息

Keeling P J, Charlebois R L, Doolittle W F

机构信息

Canadian Institute for Advanced Research, Department of Biochemistry, Dalhousie University, Halifax, Nova Scotia.

出版信息

Curr Opin Genet Dev. 1994 Dec;4(6):816-22. doi: 10.1016/0959-437x(94)90065-5.

Abstract

Since the recognition of the uniqueness and coherence of the archaebacteria (sometimes called Archaea), our perception of their role in early evolution has been modified repeatedly. The deluge of sequence data and rapidly improving molecular systematic methods have combined with a better understanding of archaebacterial molecular biology to describe a group that in some ways appears to be very similar to the eubacteria, though in others is more like the eukaryotes. The structure and contents of archaebacterial genomes are examined here, with an eye to their meaning in terms of the evolution of cell structure and function.

摘要

自从认识到古细菌(有时称为古菌)的独特性和连贯性以来,我们对它们在早期进化中所起作用的认识已多次发生改变。大量的序列数据和迅速改进的分子系统发育方法,再加上对古细菌分子生物学的更深入了解,共同描绘出这样一类生物:它们在某些方面似乎与真细菌非常相似,而在其他方面则更类似于真核生物。本文将研究古细菌基因组的结构和内容,着眼于它们在细胞结构和功能进化方面的意义。

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