Bordinazzo R, Benecchi L, Cazzaniga A, Vercesi A, Privitera O
Department of Urologic Surgery, S. Corona Hospital, Garbagnate Milanese, Milano.
Arch Ital Urol Androl. 1994 Sep;66(4 Suppl):101-6.
We retrospectively reviewed the outcome of 28 prostate cancer patients with ureteral obstruction treated by percutaneous nephrostomy. The over-all survival was 60% at 1 year and 32% at 2 years. The 1 and 2 years survival rates of 13 patients with no prior hormonal therapy were 70 and 45%, respectively, while those of patients who had previously received hormonal therapy were 46 and 17% respectively. Of 10 patients who had severe renal failure before percutaneous nephrostomy (serum creatinine greater than or equal to 7 mg per dl), 8 had an adequate return of renal function (serum creatinine less than 3 mg pe dl) after drainage and 55% survived more than 1 year, cutaneous nephrostomy is safe and effective in relieving ureteral obstruction and reasonable survival can be achieved even in patient with renal failure. Percutaneous nephrostomy should be considered strongly in these patients.
我们回顾性分析了28例因输尿管梗阻接受经皮肾造瘘术治疗的前列腺癌患者的预后。1年总生存率为60%,2年为32%。13例未接受过激素治疗患者的1年和2年生存率分别为70%和45%,而先前接受过激素治疗患者的1年和2年生存率分别为46%和17%。在经皮肾造瘘术前有严重肾衰竭(血清肌酐大于或等于7mg/dl)的10例患者中,8例在引流后肾功能得到充分恢复(血清肌酐小于3mg/dl),55%存活超过1年,经皮肾造瘘术在缓解输尿管梗阻方面安全有效,即使是肾衰竭患者也能实现合理存活。对于这些患者应强烈考虑行经皮肾造瘘术。