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[饮食改变时十二指肠腺的变化(一项使用凝集素的组织化学研究)]

[Changes in the duodenal glands with a modification of the diet (a histochemical study using lectins)].

作者信息

Iatskovskiĭ A N, Boronikhina T V, Sukhanov B P, Lutsik A D

出版信息

Morfologiia. 1993 Mar-Apr;104(3-4):112-8.

PMID:7889153
Abstract

A set of lectins with different carbohydrate specificities were used for a histochemical analysis of the duodenal glands of rats which had different food rations during 3 months. Lectin receptors in glandulocytes of the duodenum had different spectra under different food regimens: protein diets of the animals correlated with the accumulation of glycopolymers in the glandular epithelium with the terminal residues of N-acetyl-D-galactosamine, N-acetyl-D-glucosamine, L-fucose, higher content of cellulose in food was followed by reduction of fucosoglycans in combination with accumulation of mannose-containing glycopolymers. The regular specific features found point to quantitative and qualitative changes to the formed secretion of the duodenal glands under the influence of changing conditions of nutrition.

摘要

一组具有不同碳水化合物特异性的凝集素被用于对在3个月内摄入不同食物定量的大鼠十二指肠腺进行组织化学分析。在不同的饮食方案下,十二指肠腺细胞中的凝集素受体具有不同的谱型:动物的蛋白质饮食与腺上皮中含有N-乙酰-D-半乳糖胺、N-乙酰-D-葡萄糖胺、L-岩藻糖末端残基的糖聚合物积累相关,食物中纤维素含量较高时,岩藻糖聚糖减少,同时含甘露糖的糖聚合物积累。所发现的规律性特异性特征表明,在营养条件变化的影响下,十二指肠腺形成的分泌物发生了定量和定性的变化。

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