Scerri L, Zaki I, Allen B R, Golding P
Department of Dermatology, University Hospital, Queen's Medical Centre, Nottingham, UK.
Clin Exp Dermatol. 1994 Nov;19(6):523-5. doi: 10.1111/j.1365-2230.1994.tb01264.x.
Dermatomyositis (DM) is a connective tissue disorder characterized by cutaneous and muscle involvement. It is a well recognized paraneoplastic syndrome and has been linked with malignancy in 15-34% of adult patients. The course of DM in such patients usually correlates closely with the activity of the underlying malignancy. We report a patient who developed DM 4 years after excision of a malignant melanoma (MM) from the back and 1 year before the diagnosis of metastatic disease. A literature review revealed that the association of dermatomyositis with MM is rare and consistent with a dismal prognosis.
皮肌炎（DM）是一种以皮肤和肌肉受累为特征的结缔组织疾病。它是一种公认的副肿瘤综合征，在15%至34%的成年患者中与恶性肿瘤有关。此类患者的皮肌炎病程通常与潜在恶性肿瘤的活动密切相关。我们报告一名患者，其在背部恶性黑色素瘤（MM）切除术后4年、转移性疾病诊断前1年发生了皮肌炎。文献综述显示，皮肌炎与MM的关联罕见，且预后不佳。
